Hangover Research Today is a free monthly online journal that collates and summarizes the latest research about Hangover, including details on alcohol, treatment, drugs, effects.

Effect of a single early-gestational alcohol consumption on the insulin binding by immune cells of adult rats.

Pállinger E, Csaba G

Immunogenomic Research Group, Hungarian Academy of Sciences, 1445, Budapest, Hungary.

Rat dams were exposed to 15% ethanol containing water ad libitum for 24 h at the 3rd day of gestation. Adult progenies' immune cells (peritoneal, blood and thymic lymphocytes, monocyte-macrophage-granulocyte group and mast cells) were studied by flow cytometry for binding of FITC-labelled insulin (compared to the appropriate cells of untreated animals). All of the cell types studied bound significantly less insulin, except mast cells. The results call attention to the life-long effect of occasional alcohol consumption in early pregnancy manifested in the immune system.

Published 3 January 2006 in Inflamm Res, 54(12): 483-4.
Full-text of this article is available online (may require subscription).

© 2004-2008 Hangover Research Today. All Rights Reserved.